Infection of CD8+CD45RO+ Memory T-Cells by HIV-1 and Their Proliferative Response

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Infection of CD8+CD45RO+ Memory T-Cells by HIV-1 and Their Proliferative Response

CD8+ T-cells are involved in controlling HIV-1 infection by eliminating infected cells and secreting soluble factors that inhibit viral replication. To investigate the mechanism and significance of infection of CD8+ T-cells by HIV-1 in vitro, we examined the susceptibility of these cells and their subsets to infection. CD8+ T-cells supported greater levels of replication with T-cell tropic stra...

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ژورنال

عنوان ژورنال: The Open AIDS Journal

سال: 2008

ISSN: 1874-6136

DOI: 10.2174/1874613600802010043